The Signos Continuous Glucose Monitor
Signos pairs an FDA-cleared continuous glucose monitor (CGM) with an AI app that shows how food, sleep, and movement affect your glucose, so you can lose weight with real data.
What makes Signos different:
Hit Your Weight Goals
Discover Your "Fat-Loss Foods"- Get AI Nudges For Healthy Habits
- In-Your-Pocket Personalized Guidance
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HSA/FSA eligible
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What makes Signos different:
- Hit Your Weight Goals
- Discover Your "Fat-Loss Foods"
- Get AI Nudges For Healthy Habits
- In-Your-Pocket Personalized Guidance
STARTING AT
SIGNOS+ PLAN
Clinician-prescribed GLP-1 + CGM
The best choice if you're:
Ready to pair clinician-prescribed GLP-1 with real metabolic insight
Want to lose the weight, understand why, and keep it off
Looking for an all-in-one program — for the same price as medication alone from leading providers
What's included:
Personalized 3 or 6-month GLP-1 treatment plan
CGMs included to monitor progress
AI-powered companion app for GLP-1 and glucose tracking
Free, rapid shipping to your door
What makes Signos different:
- Hit Your Weight Goals
- Discover Your "Fat-Loss Foods"
- Get AI Nudges For Healthy Habits
- In-Your-Pocket Personalized Guidance
Take the 2-minute quiz and a clinician will tailor your GLP-1 plan.
How continuous glucose monitoring works
A CGM measures your glucose around the clock and sends it to your phone. Signos turns that stream of data into guidance you can act on.
- Step 01
Apply your sensor
Press the applicator to the back of your upper arm and the sensor is on in seconds. No finger pricks. Each sensor lasts 15 days.
- Step 02
Wear it and sync
Your CGM takes a glucose reading every five minutes and sends the data to the Signos app on your phone every 15 minutes via Bluetooth, day and night.
- Step 03
Act on your data
Signos scores your meals, predicts glucose spikes before they happen, and suggests the movement that brings glucose back down.
What your CGM shows you
24/7 glucose monitoring
A 15-day biosensor delivers round-the-clock glucose data straight to your app.
Spike predictions
Stay ahead of spikes with movement alerts, guiding insights, and health reports.
Dietitian support
Chat with a dietitian in-app or book a 1:1 call for personalized guidance.
Personalized AI nudges
Get predictions, personalized nudges, and pattern-spotting for serious metabolic control.
Smart food logging
Snap a pic, scan a barcode, or type it in, and Signos shows you how it affects your glucose.
Sleep and stress tracking
Your metabolism doesn't just care about food. See how stress and sleep affect your glucose, too.
A wearable glucose sensor, not a finger prick
A continuous glucose monitor is a small sensor that sits on the back of your upper arm. It replaces finger pricks with a steady stream of glucose data, so you can see what happens after every meal, workout, and night of sleep.
Every Signos plan uses the Stelo glucose biosensor by Dexcom. You apply it yourself at home, wear it for 15 days, then switch to the next one. Plans include two sensors a month.
- Sensor
- Stelo by Dexcom
- Wear time
- 15 days per sensor
- Glucose readings
- Every 5 minutes
- Finger pricks
- None
- FDA status
- FDA-cleared, OTC
- Prescription
- Not required
A CGM for people without diabetes, too
Signos is built for weight and metabolic health. You don't need a diabetes diagnosis or a prescription, just a goal and the curiosity to see how your body handles food.
Signos is a great fit if you
- Want to lose weight with real data, not guesswork
- Don't have diabetes but want to see how food affects your glucose
- Want to find your personal fat-loss foods
- Train hard and want to see how meals and workouts affect your glucose
- Want steadier energy and fewer crashes through the day
Signos isn't right for you if you
- Are under 18
- Take insulin or have problematic hypoglycemia
- Are on dialysis
- Have an active eating disorder
- Need a prescription CGM to manage diabetes
Real weight loss, published
5.1%
of body weight lost on average in six months
5.9%
among more engaged members
7.1%
among highly engaged members with a BMI of 40+
Diabetes Technology & Therapeutics, 2026: 3,007 adults with obesity, none of them diabetic and none taking GLP-1 medications, who used Signos for six months. Read about the study →
“I’ve tried diets, exercise, everything. This is the only thing that has helped me lose weight!”
-Kay C.
What customers are saying:
“I’ve tried diets, exercise, everything. This is the only thing that has helped me lose weight!”
-Kay C.
4.8
Product rating
86%
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CGM questions, answered
What is a continuous glucose monitor (CGM)?
A continuous glucose monitor (CGM) is a small wearable sensor that tracks your glucose 24/7, with no finger pricks. Instead of a single reading, you see how your glucose rises and falls throughout the day and night.
Signos pairs a CGM, the Stelo glucose biosensor by Dexcom, with an AI app that turns your readings into personalized guidance for weight and metabolic health.
How does continuous glucose monitoring work?
A thin, flexible filament just under the skin measures glucose in the fluid between your cells. The sensor takes a reading every five minutes and sends the data to your phone every 15 minutes via Bluetooth.
The Signos app combines those readings with your meals, workouts, sleep, and weight to predict spikes, score meals, and suggest what to eat or how to move next.
Can a CGM help you lose weight?
Yes, when used consistently, CGMs can support healthy, sustainable weight management by helping you understand how your body responds to food, exercise, and daily habits in real time. Research shows that 87% of CGM users change their food choices based on glucose feedback, and nearly half are more likely to move their bodies when they see a spike.
Signos takes that a step further by using your personal glucose data, meal logs, and workout history to suggest what to eat next or how to move, so you're not guessing. With consistent use, CGMs paired with in-the-moment guidance can help retrain your appetite, reduce overeating, and build habits that support long-term weight and fat loss.
In a peer-reviewed 2026 study in Diabetes Technology & Therapeutics, 3,007 Signos members with obesity, none of them diabetic and none taking GLP-1 medications, lost an average of more than 5% of their body weight in six months.
Read about the Signos clinical study →Read the research →Is a CGM painful?
Most people feel little to nothing. You apply the sensor to the back of your upper arm with an applicator in a few seconds, and there are no finger pricks after that.
How long does a CGM sensor last?
Each sensor lasts 15 days. Every Signos plan includes two sensors per month, so you have continuous coverage. Six-month plans ship in three-month bundles.
Do I need a prescription for a CGM?
No. Signos is the first and only FDA-cleared over-the-counter continuous glucose monitoring system for weight management, so you can order online without a prescription or a doctor's visit.
It's intended for adults 18 and older who are not on insulin.
How much does a CGM cost without insurance?
Signos plans start at $127/month and include two CGM sensors per month, the AI app, unlimited tracking, and in-app dietitian chat. Longer plans cost less per month.
You don't need insurance to buy Signos, and you may be able to pay with your HSA or FSA. Coverage varies, so check with your provider.
Can I use a CGM if I don't have diabetes?
Yes. Signos is built for people focused on weight and metabolic health, including people without diabetes. Seeing how your glucose responds to food, sleep, stress, and exercise helps you build habits that support weight management.
What's the difference between a CGM and a glucose meter?
A glucose meter (glucometer) needs a finger prick and gives you one reading at one moment. A CGM reads your glucose automatically every five minutes, so you see trends, spikes, and dips across the whole day, including overnight.
Can I use a CGM while taking a GLP-1?
Yes. If you're already on a GLP-1, GLP-1 Essentials is a part-time program built around your medication: six 15-day sensors over six months, worn when they count. Medication not included.
See GLP-1 Essentials →Start with the Signos CGM
Two sensors a month, the AI app, and dietitian support, from $127/month. No prescription needed.
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Copyright © 2026 Signos Inc.
Signos indications: The Signos Glucose Monitoring System is an over-the-counter (OTC) mobile device application that receives data from an integrated Continuous Glucose Monitor (iCGM) sensor and is intended to continuously measure, record, analyze, and display glucose values in people 18 years and older not on insulin. The Signos Glucose Monitoring System helps to detect normal (euglycemic) and low or high (dysglycemic) glucose levels. The Signos Glucose Monitoring System may also help the user better understand how lifestyle and behavior modification, including diet and exercise, impact glucose excursions. This information may be useful in helping users to maintain a healthy weight.
The user is not intended to take medical action based on the device output without consultation with a qualified healthcare professional.
See user guide for important warnings and precautions.
STELO IMPORTANT INFORMATION: Consult your healthcare provider before making any medication adjustments based on your sensor readings and do not take any other medical action based on your sensor readings without consulting your healthcare provider. Do not use if you have problematic hypoglycemia. Failure to use Stelo and its components according to the instructions for use provided and to properly consider all indications, contraindications, warnings, and cautions in those instructions for use may result in you missing a severe hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose) occurrence. If your sensor readings are not consistent with your symptoms, a blood glucose meter may be an option as needed and consult your healthcare provider. Seek medical advice and attention when appropriate, including before making any medication adjustments and/or for any medical emergency.
STELO INDICATIONS FOR USE: The Stelo Glucose Biosensor System is an over-the-counter (OTC) integrated Continuous Glucose Monitor (iCGM) intended to continuously measure, record, analyze, and display glucose values in people 18 years and older not on insulin. The Stelo Glucose Biosensor System helps to detect normal (euglycemic) and low or high (dysglycemic) glucose levels. The Stelo Glucose Biosensor System may also help the user better understand how lifestyle and behavior modification, including diet and exercise, impact glucose excursion. The user is not intended to take medical action based on the device output without consultation with a qualified healthcare professional.
OPENLOOP CLINICAL AND PHARMACEUTICAL SERVICES:
Signos is a technology platform and wellness program provider. With the exception of registered dieticians, Signos does not employ licensed health care professionals to practice medicine, does not diagnose, treat, cure, or prevent any disease or medical condition, and does not provide medical advice. You should always consult your own health care professional for diagnosis, treatment, and care regarding any medical condition or health concern. Clinical services accessible through the Signos platform are provided solely by OpenLoop Health and other independent networks of U.S.-licensed clinicians, who exercise their own independent medical judgment to determine eligibility for GLP‑1 treatment based on medical history and assessment responses. These independent providers retain full discretion to prescribe or decline compounded GLP‑1 medications. Signos does not direct, control, or influence any clinical decision made by these providers, and no provider-patient relationship is created between you and Signos.
Compounded medications that may be made available in connection with the Signos program are produced in FDA-registered facilities, but are not FDA-approved and have not been evaluated by the FDA for safety, efficacy, or quality. Signos does not manufacture, compound, dispense, or distribute any medications. Signos partners with certified U.S. pharmacies to help facilitate access to these medications, but Signos makes no representations or warranties regarding the safety, efficacy, suitability, or quality of any compounded medication. Product appearance may differ from website images.
Medication costs are included in the Signos program; however, inclusion of medication costs does not constitute the practice of medicine or pharmacy by Signos. Results may vary and depend on individual adherence, independent provider guidance, and lifestyle changes. Unless otherwise noted, results referenced reflect individual Signos patient experiences rather than public clinical studies, and no particular outcome is guaranteed.
Nothing on this website or within the Signos platform should be construed as medical advice, a medical diagnosis, or a recommendation for any specific treatment. If you are experiencing a medical emergency, call 911 or your local emergency services immediately.