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November 4, 2024
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Glucose
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3 min read
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Written By
Brittany Barry

It’s Not Just What You Eat; It’s When You Eat: Introducing Latest Spike Time (LST), the Newest Signos Discovery

couple eating using Signos CGM

Have you ever wondered if eating late at night impacts your weight loss success and progress? At Signos, we have data from thousands of members and started looking into the trends behind our members' glucose spikes. We noticed that Signos members who avoided glucose spikes after 6 pm were more successful with metabolic health and weight management. 

This trend propelled our scientists to more specifically analyze member data to evaluate whether this was true across our members. Nine hundred and twenty-six individuals were included in the Signos research study, and the findings were definitive: the latest spike time (LST) proved to have a strong correlation with weight loss. The study found that the individuals who had an LST before 5:40 pm lost over three times as much weight as individuals who had an LST after 8:40 pm. 

At Signos, we empower our members with data that shows them what is happening metabolically in real-time. Instead of playing the guessing game with your health, tap into data from your continuous glucose monitor (CGM) and take steps that make sense for your health situation. 

Once you become a Signos member, you will have access to Signos Insights and Reports, a dashboard where you can view trends based on all the data your CGM has collected over specific periods.

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What Are Insights?

In the Signos app, members can view trends (or insights) based on the data their continuous glucose monitor (CGM) receives. An individual’s current glucose is a great indicator of how recent actions have impacted their glucose and overall metabolic health. Other factors that impact metabolic health include insulin sensitivity, body composition (BMI), diet, sleep quality, stress levels, genetics, lifestyle factors (e.g., alcohol consumption and tobacco use), and gut health.

Insight Into Your Bio Data

Members can view six major data points in the Signos app's Insight tab. 

1. Weight

Studies show that regularly logging your weight can help you stay on track with your goals. It helps build awareness of how your body may change from week to week due to your behaviors. Though weight is just one marker of metabolic health, it can be a helpful window into your general progress.

If your goal is weight loss, medical literature suggests that losing one to two pounds per week is safe. However, check with your healthcare provider for more specific guidance if you have a special circumstance, like a chronic condition, that is actively being treated. If your goal is increased metabolic health, the aim is to maintain your current weight. 

We know your health is much more than the number on the scale, but this data point is easy to track. Daily weight can fluctuate even by a few pounds based on factors like hydration, sodium intake, foods eaten in one day, stress, and sleep. It’s most important to pay attention to your own trends over time. 

2. Average Glucose

This metric shows your average glucose over your last 30 days of readings. If you are not prediabetic or living with type 2 diabetes, you want to aim for an average glucose of 80-110. Averages can go up and down depending on various factors (what you ate that day, the day before, hydration, how well you slept, etc.). It is important to watch the overall trend of your glucose.

3. Variability

Glucose variability (GRV or GV), represented as a percentage, refers to the frequency and height of your spikes and dips in glucose throughout the day. It is calculated by looking at the ratio of the standard deviation to the mean (how much you fluctuate outside of your average range).

Your target variability will depend on your health and wellness goals. Aim to keep your GRV under 13% for weight loss and optimal metabolic health. If you are consistently below 13%, keep it up! Clinical data from research studies shows that higher GRV is associated with poorer metabolic health outcomes, while lower GRV is associated with increased lifespan independently of hemoglobin A1C levels.

4. Latest Spike Time (LST)

LST tracks the latest spike in your glucose levels daily and averages it over time. This helps you identify trends in your glucose spikes to fine-tune your approach and stay on course with your health goals. Our data shows members whose latest spike is before 6 PM lose the most weight.

5. Time in Range

Time in Range (TIR) represents the amount of time you spend within your optimal glucose range within a day. This is represented in reports as a 30-day average of your daily Time in Range. Signos data shows that being in range at least 80% of the day will drive you closer to achieving your health goals.

6. Overnight Glucose

Overnight glucose is an average of your most stable 6 hours during nighttime.  Averages can go up and down depending on various factors (e.g., consuming a higher carbohydrate meal for dinner or eating late at night, poor sleep, alcohol, and higher stress levels). It’s important to watch the overall trend of your glucose.

Aim for an average overnight glucose of 70-100 mg/dL. However, averages can fluctuate depending on various factors (e.g., consuming a higher-carbohydrate meal for dinner or eating late at night, poor sleep, alcohol, and higher stress levels). Therefore, it’s important to watch the overall trend of your glucose.

<div class="pro-tip"><strong>Learn More: </strong><a href=mitigate-high-glucose-spikes>How to Mitigate High Glucose Spikes to Avoid Fat Storage</a>.</div>

Why Is LST Important?

Signos always analyzes and improves to support members' weight loss and metabolic health. As part of this work and based on thousands of members' glucose data, Signos found that avoiding glucose spikes late in the day is extremely helpful for losing weight. To make this information available to members, Signos has implemented this new metric, Latest Spike Time(LST), in the app and published this research to benefit others. 

So What’s New?

If you see a question mark (?) on your insights graph, this is an indicator that Signos detected a meaningful spike outside of a logged meal. Signos calls these Points of Interest. The average Signos member has 2.3 POI per day. LST is the last detected POI on a given day. On the Insights page, you can view your average LST for the last seven days and your overall program length.

For optimal weight loss, Signos recommends avoiding spikes after 6 PM.

LST vs. GV and TIR

Signos provides members with many data points to help them better understand their glucose response and metabolic health. Glucose variability (GV) continues to be the best predictor for metabolic health and weight loss, but other metrics, like TIR and LST, are extremely helpful in specific circumstances.  

LST, in particular, brings attention to a specific glucose pattern, late spiking, which members may want to monitor. For example, for a member who has already improved their GV/TIR and would like to continue improving their glucose response, looking at LST may help them take the next step in their wellness journey.

If You Like To Eat Later

Signos understands that members have different schedules. Any movement in your average LST is positive, even if you do not reach 6 PM. LST centers around the concept of avoiding large spikes later in the evening. Many members can avoid these large nighttime spikes by keeping their later meals higher in protein and fat and lower in carbohydrates.

Using a CGM with Signos: Real-Time Data, Backed by AI

Signos pairs a real-time glucose biosensor with AI trained on tens of millions of data points to deliver personalized, science-backed guidance for weight management and health. See exactly how your body responds, and take action.

Learn how it works. Ready to get started? Join now.

<div class="pro-tip"><strong>Also Read: </strong><a href=how-long-lower-blood-sugar-spike>How Long Does it Take to Lower Blood Sugar Spikes? A Guide</a>.</div>

Brittany Barry

About the author

Victoria Whittington earned her Bachelor of Science in Food and Nutrition from the University of Alabama and has over 10 years of experience in the health and fitness industry.

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Terms and ConditionsPrivacy Policy

Signos indications: The Signos Glucose Monitoring System is an over-the-counter (OTC) mobile device application that uses an integrated Continuous Glucose Monitor (iCGM)
intended to continuously measure, record, analyze, and display glucose values in people 18 years and older, not on insulin. The Signos Glucose Monitoring System helps to detect
normal (euglycemic) and low or high (dysglycemic) glucose levels. The Signos Glucose Monitoring System may also help the user better understand how lifestyle and behavior modification, including diet and exercise, impact glucose excursions. This information may be useful in helping users to maintain a healthy weight.

The user is not intended to take medical action based on the device output without consultation with a qualified healthcare professional.
See user guide for important warnings and precautions.
STELO IMPORTANT INFORMATION: Consult your healthcare provider before making any medication adjustments based on your sensor readings and do not take any other medical action based on your sensor readings without consulting your healthcare provider. Do not use if you have problematic hypoglycemia. Failure to use Stelo and its components according to
the instructions for use provided and to properly consider all indications, contraindications, warnings, and cautions in those instructions for use may result in you missing a
severe hypoglycemia (low blood glucose) or hyperglycemia (high blood glucose) occurrence. If your sensor readings are not consistent with your symptoms, a blood glucose meter
may be an option as needed and consult your healthcare provider. Seek medical advice and attention when appropriate, including before making any medication adjustments and/or
for any medical emergency.
STELO INDICATIONS FOR USE: The Stelo Glucose Biosensor System is an over-the-counter (OTC) integrated Continuous Glucose Monitor (iCGM) intended to continuously measure, record, analyze, and display glucose values in people 18 years and older not on insulin. The Stelo Glucose Biosensor System helps to detect normal (euglycemic) and low or high
(dysglycemic) glucose levels. The Stelo Glucose Biosensor System may also help the user better understand how lifestyle and behavior modification, including diet and exercise,
impact glucose excursion. The user is not intended to take medical action based on the device output without consultation with a qualified healthcare professional.